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Adrenocortical expression profiling of cattle with distinct juvenile temperament types.
Autor: Friedrich, Juliane; Brand, Bodo; Graunke, Katharina L.; Langbein, Jan; Schwerin, Manfred; Ponsuksili, Siriluck
In:
Behavior Genetics
Bandangabe: 47
Auflage: 1
ISBN: 1573-3297
DOI: 10.1007/s10519-016-9816-0
Seite: 102 - 113
Jahr: 2017
Einordung:
Institut: Professur Tierzucht und Haustiergenetik
Abstract:
Temperament affects ease of handling, animal welfare, and economically important production traits in cattle. The use of gene expression profiles as molecular traits provides a novel means of gaining insight into behavioural genetics. In this study, differences in adrenocortical expression profiles between 60 F2 cows (Charolais × German Holstein) of distinct temperament types were analysed. The cows were assessed in a novel-human test at an age of 90 days. Most of the adrenal cortex transcripts which were differentially expressed (FDR <0.05) were found between temperament types of 'fearful/neophobic-alert' and all other temperament types. These transcripts belong to several biological functions like NRF2-mediated oxidative stress response, Glucocorticoid Receptor Signalling and Complement System. Overall, the present study provides new insight into transcriptional differences in the adrenal cortex between cows of distinct temperament types. Genetic regulations of such molecular traits facilitate uncovering positional and functional gene candidates for temperament type in cattle. Ansprechpartner Weitere Information im WWW
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Letzte Änderung des Eintrages:
21.04.2017
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